Continuous flow synthesis of diaryl ketones by coupling of aryl Grignard reagents with acyl chlorides under mild conditions in the ecofriendly solvent 2-methyltetrahydrofuran

An efficient continuous flow sequential synthesis of diaryl ketones was achieved by coupling of aryl Grignard reagents with acyl chlorides in the bio-derived “green” solvent 2-methyltetrahydrofuran (2-MeTHF) under mild reaction conditions (ambient temperature, 1 hour), allowing a safe and on-demand...

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Detalles Bibliográficos
Autores principales: Zhang, Chuan-Tao, Zhu, Rui, Wang, Zheng, Ma, Bing, Zajac, Adrian, Smiglak, Marcin, Xia, Chun-Nian, Castle, Steven L., Wang, Wen-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059842/
https://www.ncbi.nlm.nih.gov/pubmed/35516141
http://dx.doi.org/10.1039/c8ra07447j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059842/
https://www.ncbi.nlm.nih.gov/pubmed/35516141
http://dx.doi.org/10.1039/c8ra07447j

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