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I(2)-catalyzed intramolecular oxidative amination of C(sp(3))–H bond: efficient access to 3-acylimidazo[1,2-a]pyridines under neat condition

An efficient and “green” protocol for the synthesis of 3-acylimidazo[1,2-a]pyridines through intramolecular oxidative α-amination of carbonyl compounds has been developed. The reaction proceeds smoothly utilizing I(2) as a catalyst and H(2)O(2) as an oxidant under neat condition with broad substrate...

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Detalles Bibliográficos
Autores principales: Huang, Lilan, Yin, Wenqing, Wang, Jian, Gan, Chunfang, Huang, Yanmin, Huang, Chusheng, He, Yimiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059843/
https://www.ncbi.nlm.nih.gov/pubmed/35520479
http://dx.doi.org/10.1039/c8ra10118c