Cargando…

Sequential ligand- and structure-based virtual screening approach for the identification of potential G protein-coupled estrogen receptor-1 (GPER-1) modulators

G protein-coupled estrogen receptor-1 (GPER-1) is a seven transmembrane receptor, responsible for mediating rapid estrogen signaling in many physiological responses in reproductive, nervous, endocrine, immune and cardiovascular systems. Due to unavailability of the crystal structure of GPER-1, we ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Khan, Shafi Ullah, Ahemad, Nafees, Chuah, Lay-Hong, Naidu, Rakesh, Htar, Thet Thet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059856/
https://www.ncbi.nlm.nih.gov/pubmed/35520492
http://dx.doi.org/10.1039/c8ra09318k