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Synthesis and biological evaluation of 2,2-dimethylbenzopyran derivatives as potent neuroprotection agents

The development of novel neuroprotection agents is of great significance for the treatment of ischemic stroke. In this study, a series of compounds comprising 2,2-dimethylbenzopyran groups and cinnamic acid groups have been synthesized. Preferential combination principles and bioisostere that improv...

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Detalles Bibliográficos
Autores principales: Du, Fangyu, Zhou, Qifan, Fu, Xiaoxiao, Shi, Yajie, Chen, Yuanguang, Fang, Wuhong, Yang, Jingyu, Chen, Guoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059924/
https://www.ncbi.nlm.nih.gov/pubmed/35520520
http://dx.doi.org/10.1039/c8ra10424g