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Synthesis and biological evaluation of 2,2-dimethylbenzopyran derivatives as potent neuroprotection agents
The development of novel neuroprotection agents is of great significance for the treatment of ischemic stroke. In this study, a series of compounds comprising 2,2-dimethylbenzopyran groups and cinnamic acid groups have been synthesized. Preferential combination principles and bioisostere that improv...
Autores principales: | Du, Fangyu, Zhou, Qifan, Fu, Xiaoxiao, Shi, Yajie, Chen, Yuanguang, Fang, Wuhong, Yang, Jingyu, Chen, Guoliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059924/ https://www.ncbi.nlm.nih.gov/pubmed/35520520 http://dx.doi.org/10.1039/c8ra10424g |
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