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Efficacy and safety of secukinumab for the treatment of severe ABCA12 deficiency‐related ichthyosis in a child

BACKGROUND: Patients with severe autosomal recessive congenital ichthyosis (ARCI) show a T helper 17/interleukin 17 (Th17/IL17) skewing in their skin and serum, resembling the inflammatory profile of psoriatic patients. Secukinumab, an IL‐17A inhibitor, has shown clinical efficacy in patients with m...

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Detalles Bibliográficos
Autores principales: Yogarajah, J., Gouveia, C., Iype, J., Häfliger, S., Schaller, A., Nuoffer, J.M., Fux, M., Gautschi, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060064/
https://www.ncbi.nlm.nih.gov/pubmed/35664977
http://dx.doi.org/10.1002/ski2.25