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An efficient, mild and metal free l-proline catalyzed construction of fused pyrimidines under microwave conditions in water

One-pot condensation of 4-hydroxy coumarins, aldehydes and urea/thiourea to build C–C and C–N bonds is described. Fused pyrimidines have been synthesized under mild reaction conditions using l-proline. The protocol has been performed rapidly and efficiently in water under metal free conditions. Hete...

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Detalles Bibliográficos
Autores principales: Kaurav, Manvendra S., Sahu, Pramod K., Sahu, Praveen K., Messali, Mouslim, Almutairi, Saud M., Sahu, Puran L., Agarwal, Dau D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060310/
https://www.ncbi.nlm.nih.gov/pubmed/35518091
http://dx.doi.org/10.1039/c8ra07517d