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An efficient, mild and metal free l-proline catalyzed construction of fused pyrimidines under microwave conditions in water
One-pot condensation of 4-hydroxy coumarins, aldehydes and urea/thiourea to build C–C and C–N bonds is described. Fused pyrimidines have been synthesized under mild reaction conditions using l-proline. The protocol has been performed rapidly and efficiently in water under metal free conditions. Hete...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060310/ https://www.ncbi.nlm.nih.gov/pubmed/35518091 http://dx.doi.org/10.1039/c8ra07517d |