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A DNA-modified hydrogel for simultaneous purification, concentration and detection of targeted cfDNA in human serum

Cell-free DNA (cfDNA) in blood, which stems from the fetus of pregnant women and tumor in cancer patients, has gained attention in molecular diagnosis. However, cfDNA is less stable, and its amount in the serum is extremely low; these are critical barriers for the utilization of this resource. In th...

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Detalles Bibliográficos
Autores principales: Jiang, Xinglu, Zhao, Chenggui, Fan, Xiaobo, Xu, Wei, Zhang, Rui, Xu, Hongbo, Wu, Guoqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060316/
https://www.ncbi.nlm.nih.gov/pubmed/35518945
http://dx.doi.org/10.1039/c8ra10138h