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Efficient estimation of SNP heritability using Gaussian predictive process in large scale cohort studies
With the advent of high throughput genetic data, there have been attempts to estimate heritability from genome-wide SNP data on a cohort of distantly related individuals using linear mixed model (LMM). Fitting such an LMM in a large scale cohort study, however, is tremendously challenging due to its...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060362/ https://www.ncbi.nlm.nih.gov/pubmed/35442943 http://dx.doi.org/10.1371/journal.pgen.1010151 |