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Efficient estimation of SNP heritability using Gaussian predictive process in large scale cohort studies

With the advent of high throughput genetic data, there have been attempts to estimate heritability from genome-wide SNP data on a cohort of distantly related individuals using linear mixed model (LMM). Fitting such an LMM in a large scale cohort study, however, is tremendously challenging due to its...

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Detalles Bibliográficos
Autores principales:	Seal, Souvik, Datta, Abhirup, Basu, Saonli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060362/ https://www.ncbi.nlm.nih.gov/pubmed/35442943 http://dx.doi.org/10.1371/journal.pgen.1010151

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