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Co-amorphous palbociclib–organic acid systems with increased dissolution rate, enhanced physical stability and equivalent biosafety

The preparation of co-amorphous drug systems by adding a small molecular excipient is a promising formulation in the modern pharmaceutical industry to improve the solubility, dissolution rate, and bioavailability of poorly soluble drugs. In this study, palbociclib co-amorphous systems with organic a...

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Detalles Bibliográficos
Autores principales: Zhang, Man, Xiong, Xinnuo, Suo, Zili, Hou, Quan, Gan, Na, Tang, Peixiao, Ding, Xiaohui, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060427/
https://www.ncbi.nlm.nih.gov/pubmed/35518078
http://dx.doi.org/10.1039/c8ra09710k