Cargando…
Co-amorphous palbociclib–organic acid systems with increased dissolution rate, enhanced physical stability and equivalent biosafety
The preparation of co-amorphous drug systems by adding a small molecular excipient is a promising formulation in the modern pharmaceutical industry to improve the solubility, dissolution rate, and bioavailability of poorly soluble drugs. In this study, palbociclib co-amorphous systems with organic a...
Autores principales: | Zhang, Man, Xiong, Xinnuo, Suo, Zili, Hou, Quan, Gan, Na, Tang, Peixiao, Ding, Xiaohui, Li, Hui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060427/ https://www.ncbi.nlm.nih.gov/pubmed/35518078 http://dx.doi.org/10.1039/c8ra09710k |
Ejemplares similares
-
Combined spectroscopy methods and molecular simulations for the binding properties of trametinib to human serum albumin
por: Suo, Zili, et al.
Publicado: (2018) -
Two Novel Palbociclib-Resorcinol and Palbociclib-Orcinol Cocrystals with Enhanced Solubility and Dissolution Rate
por: Duan, Chenxin, et al.
Publicado: (2021) -
Studies of the binding properties of the food preservative thiabendazole to DNA by computer simulations and NMR relaxation
por: Sun, Qiaomei, et al.
Publicado: (2018) -
Co-amorphous solid dispersion systems of lacidipine-spironolactone with improved dissolution rate and enhanced physical stability
por: Wang, Zhaomeng, et al.
Publicado: (2019) -
Image-based dissolution analysis for tracking the surface stability of amorphous powders
por: Štukelj, Jernej, et al.
Publicado: (2020)