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Hemogenic and aortic endothelium arise from a common hemogenic angioblast precursor and are specified by the Etv2 dosage
Hematopoietic stem cells (HSCs) are generated from hemogenic endothelial cells (HECs) in the floor of the dorsal aorta (DA) via endothelial-to-hematopoietic transition (EHT). Yet whether HECs and conventional endothelial cells (cECs) in the DA share a common precursor is controversial, and the molec...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060440/ https://www.ncbi.nlm.nih.gov/pubmed/35333649 http://dx.doi.org/10.1073/pnas.2119051119 |