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Hemogenic and aortic endothelium arise from a common hemogenic angioblast precursor and are specified by the Etv2 dosage

Hematopoietic stem cells (HSCs) are generated from hemogenic endothelial cells (HECs) in the floor of the dorsal aorta (DA) via endothelial-to-hematopoietic transition (EHT). Yet whether HECs and conventional endothelial cells (cECs) in the DA share a common precursor is controversial, and the molec...

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Detalles Bibliográficos
Autores principales:	Zhao, Shizheng, Feng, Shachuan, Tian, Ye, Wen, Zilong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060440/ https://www.ncbi.nlm.nih.gov/pubmed/35333649 http://dx.doi.org/10.1073/pnas.2119051119

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