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Lipoproteome screening of the Lyme disease agent identifies inhibitors of antibody-mediated complement killing

Spirochetal pathogens, such as the causative agent of Lyme disease, Borrelia burgdorferi sensu lato, encode an abundance of lipoproteins; however, due in part to their evolutionary distance from more well-studied bacteria, such as Proteobacteria and Firmicutes, few spirochetal lipoproteins have assi...

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Detalles Bibliográficos
Autores principales: Pereira, Michael J., Wager, Beau, Garrigues, Ryan J., Gerlach, Eva, Quinn, Joshua D., Dowdell, Alexander S., Osburne, Marcia S., Zückert, Wolfram R., Kraiczy, Peter, Garcia, Brandon L., Leong, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060444/
https://www.ncbi.nlm.nih.gov/pubmed/35312359
http://dx.doi.org/10.1073/pnas.2117770119