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A vasculature niche orchestrates stromal cell phenotype through PDGF signaling: Importance in human fibrotic disease

Fibrosis is characterized by excessive matrix protein accumulation and contributes to significant morbidity and mortality in the Western world. The relative lack of effective antifibrotic therapeutics for the majority of these conditions reflects the difficulty in identifying targets for human fibro...

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Detalles Bibliográficos
Autores principales: Layton, Thomas B., Williams, Lynn, Yang, Nan, Zhang, Mingjun, Lee, Carl, Feldmann, Marc, Trujillo, Glenda, Furniss, Dominic, Nanchahal, Jagdeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060460/
https://www.ncbi.nlm.nih.gov/pubmed/35320046
http://dx.doi.org/10.1073/pnas.2120336119