sEH-derived metabolites of linoleic acid drive pathologic inflammation while impairing key innate immune cell function in burn injury

Fatty acid composition in the Western diet has shifted from saturated to polyunsaturated fatty acids (PUFAs), and specifically to linoleic acid (LA, 18:2), which has gradually increased in the diet over the past 50 y to become the most abundant dietary fatty acid in human adipose tissue. PUFA-derive...

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Detalles Bibliográficos
Autores principales: Bergmann, Christian B., McReynolds, Cindy B., Wan, Debin, Singh, Nalin, Goetzman, Holly, Caldwell, Charles C., Supp, Dorothy M., Hammock, Bruce D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060469/
https://www.ncbi.nlm.nih.gov/pubmed/35312372
http://dx.doi.org/10.1073/pnas.2120691119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060469/
https://www.ncbi.nlm.nih.gov/pubmed/35312372
http://dx.doi.org/10.1073/pnas.2120691119

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