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sEH-derived metabolites of linoleic acid drive pathologic inflammation while impairing key innate immune cell function in burn injury
Fatty acid composition in the Western diet has shifted from saturated to polyunsaturated fatty acids (PUFAs), and specifically to linoleic acid (LA, 18:2), which has gradually increased in the diet over the past 50 y to become the most abundant dietary fatty acid in human adipose tissue. PUFA-derive...
Autores principales: | Bergmann, Christian B., McReynolds, Cindy B., Wan, Debin, Singh, Nalin, Goetzman, Holly, Caldwell, Charles C., Supp, Dorothy M., Hammock, Bruce D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060469/ https://www.ncbi.nlm.nih.gov/pubmed/35312372 http://dx.doi.org/10.1073/pnas.2120691119 |
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