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Sideroflexin 4 is a complex I assembly factor that interacts with the MCIA complex and is required for the assembly of the ND2 module
Sideroflexins (SFXNs) comprise a family of five paralogous proteins (SFXN1–5) in metazoan species. SFXN1/2/3 function as mitochondrial serine transporters and are required for efficient mitochondrial one-carbon (1C) metabolism. SFXN4 is evolutionarily divergent, and mutations in SFXN4 give rise to m...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060475/ https://www.ncbi.nlm.nih.gov/pubmed/35333655 http://dx.doi.org/10.1073/pnas.2115566119 |