Sideroflexin 4 is a complex I assembly factor that interacts with the MCIA complex and is required for the assembly of the ND2 module

Sideroflexins (SFXNs) comprise a family of five paralogous proteins (SFXN1–5) in metazoan species. SFXN1/2/3 function as mitochondrial serine transporters and are required for efficient mitochondrial one-carbon (1C) metabolism. SFXN4 is evolutionarily divergent, and mutations in SFXN4 give rise to m...

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Detalles Bibliográficos
Autores principales: Jackson, Thomas D., Crameri, Jordan J., Muellner-Wong, Linden, Frazier, Ann E., Palmer, Catherine S., Formosa, Luke E., Hock, Daniella H., Fujihara, Kenji M., Stait, Tegan, Sharpe, Alice J., Thorburn, David R., Ryan, Michael T., Stroud, David A., Stojanovski, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060475/
https://www.ncbi.nlm.nih.gov/pubmed/35333655
http://dx.doi.org/10.1073/pnas.2115566119

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