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Photopharmacological modulation of native CRAC channels using azoboronate photoswitches

Store-operated calcium entry through calcium release–activated calcium (CRAC) channels replenishes intracellular calcium stores and plays a critical role in cellular calcium signaling. CRAC channels are activated by tightly regulated interaction between the endoplasmic reticulum (ER) calcium sensor...

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Detalles Bibliográficos
Autores principales: Udasin, Ronald, Sil, Anwesha, Zomot, Elia, Cohen, Hadas Achildiev, Haj, Jozafina, Engelmayer, Nurit, Lev, Shaya, Binshtok, Alexander M., Shaked, Yuval, Kienzler, Michael A., Palty, Raz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060504/
https://www.ncbi.nlm.nih.gov/pubmed/35312368
http://dx.doi.org/10.1073/pnas.2118160119