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Photopharmacological modulation of native CRAC channels using azoboronate photoswitches
Store-operated calcium entry through calcium release–activated calcium (CRAC) channels replenishes intracellular calcium stores and plays a critical role in cellular calcium signaling. CRAC channels are activated by tightly regulated interaction between the endoplasmic reticulum (ER) calcium sensor...
Autores principales: | Udasin, Ronald, Sil, Anwesha, Zomot, Elia, Cohen, Hadas Achildiev, Haj, Jozafina, Engelmayer, Nurit, Lev, Shaya, Binshtok, Alexander M., Shaked, Yuval, Kienzler, Michael A., Palty, Raz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060504/ https://www.ncbi.nlm.nih.gov/pubmed/35312368 http://dx.doi.org/10.1073/pnas.2118160119 |
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