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Elastic mucus strands impair mucociliary clearance in cystic fibrosis pigs

Defective mucociliary transport contributes to infections and inflammation that destroy cystic fibrosis (CF) lungs. To better understand mechanisms that impair mucociliary transport, we tracked insufflated microdisks with X-ray computed tomography in spontaneously breathing CF pigs. Aerosolized sali...

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Detalles Bibliográficos
Autores principales: Pino-Argumedo, Maria I., Fischer, Anthony J., Hilkin, Brieanna M., Gansemer, Nicholas D., Allen, Patrick D., Hoffman, Eric A., Stoltz, David A., Welsh, Michael J., Abou Alaiwa, Mahmoud H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060506/
https://www.ncbi.nlm.nih.gov/pubmed/35324331
http://dx.doi.org/10.1073/pnas.2121731119