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Recombinant l-glutaminase obtained from Geobacillus thermodenitrificans DSM-465: characterization and in silico elucidation of conserved structural domains

Glutaminase (GLS) is an enzyme essential for amino acid metabolism; in particular, it acts as a catalyst in glutaminolysis, a reaction exploited by the malignant cells to meet the nutrient requirements for their accelerated growth and proliferation. Via regulating the initial reaction of the glutami...

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Detalles Bibliográficos
Autores principales: Shah, Luqman, Nadeem, Muhammad Shahid, Khan, Jalaluddin Azam, Zeyadi, Mustafa A., Zamzami, Mazin A., Mohammed, Kaleemuddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060542/
https://www.ncbi.nlm.nih.gov/pubmed/35520186
http://dx.doi.org/10.1039/c8ra04740e