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Recombinant l-glutaminase obtained from Geobacillus thermodenitrificans DSM-465: characterization and in silico elucidation of conserved structural domains
Glutaminase (GLS) is an enzyme essential for amino acid metabolism; in particular, it acts as a catalyst in glutaminolysis, a reaction exploited by the malignant cells to meet the nutrient requirements for their accelerated growth and proliferation. Via regulating the initial reaction of the glutami...
Autores principales: | Shah, Luqman, Nadeem, Muhammad Shahid, Khan, Jalaluddin Azam, Zeyadi, Mustafa A., Zamzami, Mazin A., Mohammed, Kaleemuddin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060542/ https://www.ncbi.nlm.nih.gov/pubmed/35520186 http://dx.doi.org/10.1039/c8ra04740e |
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