Modulation of aggregation with an electric field; scientific roadmap for a potential non-invasive therapy against tauopathies

Toxic aggregation of tau protein to neurofibrillary tangles (NFTS) is a central pathological event involved in tauopathies. Inhibition of tau protein aggregation can serve as a straightforward therapeutic strategy. However, tau-based therapeutic solutions are not very common. Phenothiazine methylene...

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Detalles Bibliográficos
Autores principales: Pandey, Gaurav, Morla, Sudhir, Nemade, Harshal B., Kumar, Sachin, Ramakrishnan, Vibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060620/
https://www.ncbi.nlm.nih.gov/pubmed/35514655
http://dx.doi.org/10.1039/c8ra09993f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060620/
https://www.ncbi.nlm.nih.gov/pubmed/35514655
http://dx.doi.org/10.1039/c8ra09993f

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