The effect of solution environment and the electrostatic factor on the crystallisation of desmotropes of irbesartan

The experimental conditions necessary for stabilising irbesartan (IBS) tautomers in solution and selectively obtaining the desmotropic crystal forms are presented herein. 1H and 2H tautomers were stabilized in specific solution conditions and the 2H-tetrazole⋯imidazole interaction was confirmed by s...

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Detalles Bibliográficos
Autores principales: Araya-Sibaja, Andrea M., Urgellés, Mariola, Vásquez-Castro, Felipe, Vargas-Huertas, Felipe, Vega-Baudrit, José Roberto, Guillén-Girón, Teodolito, Navarro-Hoyos, Mirtha, Cuffini, Silvia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060688/
https://www.ncbi.nlm.nih.gov/pubmed/35514656
http://dx.doi.org/10.1039/c8ra10146a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060688/
https://www.ncbi.nlm.nih.gov/pubmed/35514656
http://dx.doi.org/10.1039/c8ra10146a

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