Significant role of Asn-247 and Arg-64 residues in close proximity of the active site in maintaining the catalytic function of CTX-M-15 type β-lactamase

Members of Enterobacteriaceae cause antibiotic-resistant infections worldwide. One such marker, CTX-M-15, expressed by Enterobacteriaceae produces β-lactamases, which hydrolyze the cephalosporin group of antibiotics, such as cefotaxime, used in the treatment of both Gram-positive and negative bacter...

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Detalles Bibliográficos
Autores principales: Maryam, Lubna, Khalid, Shamsi, Ali, Abid, Khan, Asad U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060699/
https://www.ncbi.nlm.nih.gov/pubmed/35515906
http://dx.doi.org/10.1039/c8ra10313e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060699/
https://www.ncbi.nlm.nih.gov/pubmed/35515906
http://dx.doi.org/10.1039/c8ra10313e

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