In silico post-SELEX screening and experimental characterizations for acquisition of high affinity DNA aptamers against carcinoembryonic antigen

DNA aptamers against carcinoembryonic antigen (CEA) have been identified through the systematic evolution of ligands by exponential enrichment (SELEX) technique, but their affinity needs to be improved. In this study, an in silico approach was firstly used to screen the mutation sequences of a repor...

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Detalles Bibliográficos
Autores principales: Wang, Qiong-Lin, Cui, Hui-Fang, Du, Jiang-Feng, Lv, Qi-Yan, Song, Xiaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060916/
https://www.ncbi.nlm.nih.gov/pubmed/35517255
http://dx.doi.org/10.1039/c8ra10163a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060916/
https://www.ncbi.nlm.nih.gov/pubmed/35517255
http://dx.doi.org/10.1039/c8ra10163a

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