COX-2/sEH Dual Inhibitor PTUPB Attenuates Epithelial-Mesenchymal Transformation of Alveolar Epithelial Cells via Nrf2-Mediated Inhibition of TGF-β1/Smad Signaling

BACKGROUND: Arachidonic acid (ARA) metabolites are involved in the pathogenesis of epithelial-mesenchymal transformation (EMT). However, the role of ARA metabolism in the progression of EMT during pulmonary fibrosis (PF) has not been fully elucidated. The purpose of this study was to investigate the...

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Detalles Bibliográficos
Autores principales: Zhang, Chen-Yu, Guan, Xin-Xin, Song, Zhuo-Hui, Jiang, Hui-Ling, Liu, Yu-Biao, Chen, Ping, Duan, Jia-Xi, Zhou, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060975/
https://www.ncbi.nlm.nih.gov/pubmed/35509835
http://dx.doi.org/10.1155/2022/5759626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060975/
https://www.ncbi.nlm.nih.gov/pubmed/35509835
http://dx.doi.org/10.1155/2022/5759626

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