Simvastatin Inhibits NLRP3 Inflammasome Activation and Ameliorates Lung Injury in Hyperoxia-Induced Bronchopulmonary Dysplasia via the KLF2-Mediated Mechanism

Bronchopulmonary dysplasia (BPD) is a chronic lung disease commonly found in premature infants. Excessive inflammation and oxidative stress contribute to BPD occurrence and development. Simvastatin, as an inhibitor of HMG-CoA reductase, has been reported to have antioxidative and anti-inflammatory e...

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Detalles Bibliográficos
Autores principales: Wang, Xinye, Huo, Ran, Liang, Zhongjie, Xu, Congcong, Chen, Tingting, Lin, Jingjing, Li, Luyao, Lin, Wei, Pan, Bingting, Fu, Xiaoqin, Chen, Shangqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060986/
https://www.ncbi.nlm.nih.gov/pubmed/35509841
http://dx.doi.org/10.1155/2022/8336070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9060986/
https://www.ncbi.nlm.nih.gov/pubmed/35509841
http://dx.doi.org/10.1155/2022/8336070

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