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Observation of the generation of peroxynitrite in mouse liver after acetaminophen overdose with a boronate-based ratiometric fluorescence probe
A ratiometric fluorescent probe, BTPB, for the selective monitoring of hepatic peroxynitrite (ONOO(−)) in situ after acetaminophen (APAP) overdose has been developed. Our study provided direct evidence for supporting the generation of ONOO(−) in APAP-induced liver injury. This new probe will be a us...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061049/ https://www.ncbi.nlm.nih.gov/pubmed/35518452 http://dx.doi.org/10.1039/c8ra10053e |