Synergistic bactericide and antibiotic effects of dimeric, tetrameric, or palindromic peptides containing the RWQWR motif against Gram-positive and Gram-negative strains

Dimeric and tetrameric peptides derived from LfcinB (20–25): RRWQWR, LfcinB (20–30): RRWQWRMKKLG, LfcinB (17–31): FKARRWQWRMKKLGA, or the palindromic sequence LfcinB (21–25)(Pal): RWQWRWQWR were obtained by means of the SPPS-Fmoc/tBu methodology. The antibacterial activity of these molecules was eva...

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Detalles Bibliográficos
Autores principales: Vargas-Casanova, Yerly, Rodríguez-Mayor, Andrea Verónica, Cardenas, Karen Johanna, Leal-Castro, Aura Lucía, Muñoz-Molina, Liliana Constanza, Fierro-Medina, Ricardo, Rivera-Monroy, Zuly Jenny, García-Castañeda, Javier Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061098/
https://www.ncbi.nlm.nih.gov/pubmed/35519960
http://dx.doi.org/10.1039/c9ra00708c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061098/
https://www.ncbi.nlm.nih.gov/pubmed/35519960
http://dx.doi.org/10.1039/c9ra00708c

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