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Synergistic bactericide and antibiotic effects of dimeric, tetrameric, or palindromic peptides containing the RWQWR motif against Gram-positive and Gram-negative strains
Dimeric and tetrameric peptides derived from LfcinB (20–25): RRWQWR, LfcinB (20–30): RRWQWRMKKLG, LfcinB (17–31): FKARRWQWRMKKLGA, or the palindromic sequence LfcinB (21–25)(Pal): RWQWRWQWR were obtained by means of the SPPS-Fmoc/tBu methodology. The antibacterial activity of these molecules was eva...
Autores principales: | Vargas-Casanova, Yerly, Rodríguez-Mayor, Andrea Verónica, Cardenas, Karen Johanna, Leal-Castro, Aura Lucía, Muñoz-Molina, Liliana Constanza, Fierro-Medina, Ricardo, Rivera-Monroy, Zuly Jenny, García-Castañeda, Javier Eduardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061098/ https://www.ncbi.nlm.nih.gov/pubmed/35519960 http://dx.doi.org/10.1039/c9ra00708c |
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