Direct synthesis of 2-oxo-acetamidines from methyl ketones, aromatic amines and DMF via copper-catalyzed C(sp(3))–H amidination

A convenient method for the synthesis of 2-oxo-acetamidines from methyl ketones using aromatic amines and DMF as nitrogen sources is reported via copper-catalyzed C(sp(3))–H amidination. Various methyl ketones react readily with aromatic amines and DMF, producing 2-oxo-acetamidines in yields of 47 t...

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Detalles Bibliográficos
Autores principales: Xie, Dianke, He, Wei, Xiao, Jiang, Wu, Yao, Guo, Yongjia, Liu, Qiang, Guo, Cancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061129/
https://www.ncbi.nlm.nih.gov/pubmed/35519951
http://dx.doi.org/10.1039/c9ra00616h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061129/
https://www.ncbi.nlm.nih.gov/pubmed/35519951
http://dx.doi.org/10.1039/c9ra00616h

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