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Direct synthesis of 2-oxo-acetamidines from methyl ketones, aromatic amines and DMF via copper-catalyzed C(sp(3))–H amidination

A convenient method for the synthesis of 2-oxo-acetamidines from methyl ketones using aromatic amines and DMF as nitrogen sources is reported via copper-catalyzed C(sp(3))–H amidination. Various methyl ketones react readily with aromatic amines and DMF, producing 2-oxo-acetamidines in yields of 47 t...

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Detalles Bibliográficos
Autores principales:	Xie, Dianke, He, Wei, Xiao, Jiang, Wu, Yao, Guo, Yongjia, Liu, Qiang, Guo, Cancheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061129/ https://www.ncbi.nlm.nih.gov/pubmed/35519951 http://dx.doi.org/10.1039/c9ra00616h

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