A methanol and protic ionic liquid Ugi multicomponent reaction path to cytotoxic α-phenylacetamido amides

The Ugi four component reaction of an aldehyde, amine, isocyanide and an ethanoic acid was effected smoothly in protic ionic liquids ethylammonium nitrate (EAN) and propylammonium nitrate (PAN) to afford analogues of α-phenylacetamido amides in good to excellent isolated yields. The corresponding re...

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Detalles Bibliográficos
Autores principales: Al Otaibi, Ahmed, Deane, Fiona M., Russell, Cecilia C., Hizartzidis, Lacey, McCluskey, Siobhann N., Sakoff, Jennette A., McCluskey, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061180/
https://www.ncbi.nlm.nih.gov/pubmed/35521167
http://dx.doi.org/10.1039/c9ra00118b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061180/
https://www.ncbi.nlm.nih.gov/pubmed/35521167
http://dx.doi.org/10.1039/c9ra00118b

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