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Chemical and biological study of aplysiatoxin derivatives showing inhibition of potassium channel Kv1.5

Three new aplysiatoxins, neo-debromoaplysiatoxin D (1), oscillatoxin E (2) and oscillatoxin F (3), accompanied by four known analogues (4–7), were identified from the marine cyanobacterium Lyngbya sp. Structural frames differ amongst these metabolites, and therefore we classified compounds 1 and 4–6...

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Detalles Bibliográficos
Autores principales: Tang, Yang-Hua, Wu, Jing, Fan, Ting-Ting, Zhang, Hui-Hui, Gong, Xiao-Xia, Cao, Zheng-Yu, Zhang, Jian, Lin, Hou-Wen, Han, Bing-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061199/
https://www.ncbi.nlm.nih.gov/pubmed/35521179
http://dx.doi.org/10.1039/c9ra00965e