Engineering O-glycosylation in modified N-linked oligosaccharide (Man(12)GlcNAc(2)∼Man(16)GlcNAc(2)) Pichia pastoris strains

Yeast have been engineered for the production of therapeutic glycoproteins with humanized N-linked oligosaccharides. Both N- and O-linked oligosaccharides engineered yeast have been attractive prospects, since yeast-specific O-mannosylated proteins were reported to induce an aberrant immune response...

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Detalles Bibliográficos
Autores principales: Li, Siqiang, Sun, Peng, Gong, Xin, Chang, Shaohong, Li, Enzhong, Xu, Yuanhong, Wu, Jun, Liu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061240/
https://www.ncbi.nlm.nih.gov/pubmed/35518704
http://dx.doi.org/10.1039/c8ra08121b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061240/
https://www.ncbi.nlm.nih.gov/pubmed/35518704
http://dx.doi.org/10.1039/c8ra08121b

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