Cargando…
Engineering O-glycosylation in modified N-linked oligosaccharide (Man(12)GlcNAc(2)∼Man(16)GlcNAc(2)) Pichia pastoris strains
Yeast have been engineered for the production of therapeutic glycoproteins with humanized N-linked oligosaccharides. Both N- and O-linked oligosaccharides engineered yeast have been attractive prospects, since yeast-specific O-mannosylated proteins were reported to induce an aberrant immune response...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061240/ https://www.ncbi.nlm.nih.gov/pubmed/35518704 http://dx.doi.org/10.1039/c8ra08121b |