An miRNA derived from amelogenin exon4 regulates expression of transcription factor Runx2 by directly targeting upstream activators Nfia and Prkch

Amel, the gene encoding the amelogenin protein involved in enamel formation, is highly alternatively spliced. When exon4 is excised, it can form a mature miRNA (miR-exon4) that has previously been suggested to indirectly regulate expression of the Runt-related transcription factor 2 (Runx2) involved...

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Detalles Bibliográficos
Autores principales: Shemirani, Rozana, Lin, Gan, Abduweli Uyghurturk, Dawud, Le, Michael, Nakano, Yukiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061250/
https://www.ncbi.nlm.nih.gov/pubmed/35271849
http://dx.doi.org/10.1016/j.jbc.2022.101807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061250/
https://www.ncbi.nlm.nih.gov/pubmed/35271849
http://dx.doi.org/10.1016/j.jbc.2022.101807

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