FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation

FBXW2 is a poorly characterized F-box protein, as a tumor suppressor that inhibits growth and metastasis of lung cancer by promoting ubiquitylation and degradation of oncogenic proteins, including SKP2 and β-catenin. However, what the biological functions of FBXW2 in prostate cancer cells and whethe...

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Detalles Bibliográficos
Autores principales: Zhou, Tao, Chen, Tingting, Lai, Bin, Zhang, Wenfeng, Luo, Xi, Xia, Ding, Fu, Weihua, Xu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061686/
https://www.ncbi.nlm.nih.gov/pubmed/35499593
http://dx.doi.org/10.1007/s00018-022-04320-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061686/
https://www.ncbi.nlm.nih.gov/pubmed/35499593
http://dx.doi.org/10.1007/s00018-022-04320-3

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