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An epigenetic association analysis of childhood trauma in psychosis reveals possible overlap with methylation changes associated with PTSD

Patients with a severe mental disorder report significantly higher levels of childhood trauma (CT) than healthy individuals. Studies have suggested that CT may affect brain plasticity through epigenetic mechanisms and contribute to developing various psychiatric disorders. We performed a blood-based...

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Detalles Bibliográficos
Autores principales: Løkhammer, Solveig, Stavrum, Anne-Kristin, Polushina, Tatiana, Aas, Monica, Ottesen, Akiah A., Andreassen, Ole A., Melle, Ingrid, Le Hellard, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061740/
https://www.ncbi.nlm.nih.gov/pubmed/35501310
http://dx.doi.org/10.1038/s41398-022-01936-8