A lysosome-targetable fluorescent probe for the simultaneous sensing of Cys/Hcy and GSH from different emission channels

A lysosome-specific fluorescent probe, Lyso-AC, for biothiols was developed by incorporation of a 4-nitrophenol moiety into a coumarin dye. The Cys/Hcy-triggered substitution-rearrangement cascade, and GSH-induced substitution reaction lead to the corresponding blue emissive amino-coumarin and yello...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Xu, Lizhen, Li, Wenxiu, Chen, Wenqiang, Xiao, Qi, Huang, Jun, Huang, Chusheng, Sheng, Jiarong, Song, Xiangzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061761/
https://www.ncbi.nlm.nih.gov/pubmed/35521186
http://dx.doi.org/10.1039/c9ra00210c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061761/
https://www.ncbi.nlm.nih.gov/pubmed/35521186
http://dx.doi.org/10.1039/c9ra00210c

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