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A lysosome-targetable fluorescent probe for the simultaneous sensing of Cys/Hcy and GSH from different emission channels
A lysosome-specific fluorescent probe, Lyso-AC, for biothiols was developed by incorporation of a 4-nitrophenol moiety into a coumarin dye. The Cys/Hcy-triggered substitution-rearrangement cascade, and GSH-induced substitution reaction lead to the corresponding blue emissive amino-coumarin and yello...
Autores principales: | Zhang, Hui, Xu, Lizhen, Li, Wenxiu, Chen, Wenqiang, Xiao, Qi, Huang, Jun, Huang, Chusheng, Sheng, Jiarong, Song, Xiangzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061761/ https://www.ncbi.nlm.nih.gov/pubmed/35521186 http://dx.doi.org/10.1039/c9ra00210c |
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