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Statistical parametrization of cell cytoskeleton reveals lung cancer cytoskeletal phenotype with partial EMT signature

Epithelial–mesenchymal Transition (EMT) is a multi-step process that involves cytoskeletal rearrangement. Here, developing and using an image quantification tool, Statistical Parametrization of Cell Cytoskeleton (SPOCC), we have identified an intermediate EMT state with a specific cytoskeletal signa...

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Detalles Bibliográficos
Autores principales: Basu, Arkaprabha, Paul, Manash K., Alioscha-Perez, Mitchel, Grosberg, Anna, Sahli, Hichem, Dubinett, Steven M., Weiss, Shimon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061773/
https://www.ncbi.nlm.nih.gov/pubmed/35501466
http://dx.doi.org/10.1038/s42003-022-03358-0