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Structural mechanism of DNA-mediated Nanog–Sox2 cooperative interaction

The efficiency of stem cell transcriptional regulation always depends on the cooperative association and expression of transcription factors (TFs). Among these, Oct4, Sox2, and Nanog play major roles. Their cooperativity is facilitated via direct protein–protein interactions or DNA-mediated interact...

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Detalles Bibliográficos
Autores principales: Yesudhas, Dhanusha, Anwar, Muhammad Ayaz, Choi, Sangdun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061787/
https://www.ncbi.nlm.nih.gov/pubmed/35521171
http://dx.doi.org/10.1039/c8ra10085c