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Structure-dependent recruitment and diffusion of guest proteins in liquid droplets of FUS

Liquid droplets of a host protein, formed by liquid–liquid phase separation, recruit guest proteins and provide functional fields. Recruitment into p53 droplets is similar between disordered and folded guest proteins, whereas the diffusion of guest proteins inside droplets depends on their structura...

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Detalles Bibliográficos
Autores principales: Kamagata, Kiyoto, Iwaki, Nanako, Kanbayashi, Saori, Banerjee, Trishit, Chiba, Rika, Gaudon, Virginie, Castaing, Bertrand, Sakomoto, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061845/
https://www.ncbi.nlm.nih.gov/pubmed/35501371
http://dx.doi.org/10.1038/s41598-022-11177-w