Engineering Vascularized Islet Macroencapsulation Devices: An in vitro Platform to Study Oxygen Transport in Perfused Immobilized Pancreatic Beta Cell Cultures

Islet encapsulation devices serve to deliver pancreatic beta cells to type 1 diabetic patients without the need for chronic immunosuppression. However, clinical translation is hampered by mass transport limitations causing graft hypoxia. This is exacerbated in devices relying only on passive diffusi...

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Detalles Bibliográficos
Autores principales: S. A., Fernandez, K. S., Champion, L., Danielczak, M., Gasparrini, S., Paraskevas, R. L., Leask, C. A., Hoesli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061948/
https://www.ncbi.nlm.nih.gov/pubmed/35519615
http://dx.doi.org/10.3389/fbioe.2022.884071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061948/
https://www.ncbi.nlm.nih.gov/pubmed/35519615
http://dx.doi.org/10.3389/fbioe.2022.884071

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